Ingabe izidakamizwa zinciphisa inani lesidoda?

Abantu abaningi abathatha imithi nsuku zonke bezelapha izifo ezahlukene bavame ukukhathazeka ngemiphumela emibi yale mithi. Okunye ukukhathazeka okukhulu kwabantu abaningi ukuthi ingabe imithi inganciphisa inani lesidoda noma ingabangela ukungazali emadodeni.

Lokhu kuyinkinga enesisindo ngoba imithi ehlukene ingalimaza impilo yokuzala, okuhlanganisa nokubangela inani lesidoda eliphansi. Uma uzama ukukhulelwa, kubalulekile ukuba uqonde imiphumela emibi yemithi ehlukene esimeni sakho sokuzala.

Kodwa ingabe imithi yehlisa inani lesidoda? Iyiphi imithi ebangela ukuthi inani lesidoda lehle? Iyiphi imithi ethinteka ikhwalithi yesidoda?

Lesi sihloko sizokuhola mayelana nokubaluleka kwenani lesidoda ekuzaleni futhi sichaze imiphumela emibi yemithi ehlukene enanini lesidoda.

Inani Lesidoda Ekuzaleni Kowesilisa

Ungachaza inani lesidoda njengobuningi bamaseli esidoda akhona kumthamo othile woketshezi lwesidoda. Inani lesidoda elijwayelekile yizigidi eziyi-15 zamasidoda ngomamililitha owodwa woketshezi lwesidoda [1].

Inani lesidoda elijwayelekile liyisici esibalulekile ekuzaleni kowesilisa, kanti inani lesidoda eliphansi linganciphisa kakhulu amathuba okukhulelwa. Izinto ezahlukene zingabangela inani lesidoda eliphansi futhi zithinte ukuzala kwamadoda, njengemvelo abahlala kuyo, ukudla, indlela yokuphila, nezimo ezahlukene zempilo.

Nokho, esinye isici esikhulu esingaba nomthelela omkhulu enanini lesidoda kanye namathuba okukhulelwa yimithi. Ubufakazi bukhombisa ukuthi imithi ehlukahlukene ebhalwa odokotela kanye nemithi yokuzijabulisa ingathinta inani lesidoda.

Imithi Yokuzijabulisa Nenani Lesidoda

Imithi ebangela ukungazali emadodeni ivamise ukuba imithi yokuzijabulisa, njenge-insangu, ikokeyini, nama-anabolic steroid, ngoba ingathinta kabi inani lesidoda. Le mithi ithinta inani lesidoda nekhwalithi yaso ngokuphazamisa amazinga amahormone emzimbeni.

Ake sixoxe ngeminye imithi yokuzijabulisa ehlukene kanye nomthelela wayo enanini lesidoda ngokuningiliziwe:

1. Insangu

Ucwaningo lwango-2021 lwe-Cureus Journal lukhombisa ukuthi insangu inomthelela omubi ezicini ezahlukene zamasidoda [2]. Ucwaningo lukhombisa ukuthi lesi sidakamizwa singalimaza inani lesidoda, ukunyakaza kwamasidoda, kanye nokwakheka kwamasidoda.

Izifundo zikhombisa ukuthi insangu yehlisa amazinga e-testosterone [3]. Lona ungomunye wemikhuba echaza imiphumela emibi yesangu enanini lesidoda nempilo yesidoda iyonkana. Lesi sidakamizwa singaphinde sithinte isifiso socansi futhi sinikele ekungasebenzi kahle ocansini.

2. Methamphetamines

Odokotela bavame ukubhala i-methamphetamine ukwelapha isifo sokunganaki esihambisana nokusebenza ngokweqile, okuyi-attention-deficit hyperactivity disorder noma i-ADHD. Nokho, abantu abaningi bayisebenzisa kabi le mithi ngenxa yemiphumela yayo yokuvuselela, okungaholela ekungazaleni kowesilisa.

Izifundo zikhombisa ukuthi i-methamphetamine ingadala ukwehla kwenani lesidoda [4]. Ingaphinde ithinte ukunyakaza kwamasidoda nokwakheka kwamasidoda [5].

3. Ikokeyini

Izifundo zibonisa ukuthi ukusetshenziswa kabi kwe-cocaine kuthinta kabi inqubo yokwakheka kwesidoda futhi kunganciphisa ukugxila kwesidoda kumchamo wesidoda [6].

Elinye ibhuku locwaningo ngomthelela we-cocaine ekuzaleni kowesilisa libonisa ukuthi i-cocaine inganciphisa isifiso socansi futhi iholele ekungami kahle [7].

4. Utswala

Utswala lungenye yezidakamizwa zokuzijabulisa ezisetshenziswa kakhulu emhlabeni. Utswala lungathinta ukuzala kowesilisa ngezindlela eziningi.

Ucwaningo lwango-2021 ngomthelela wokuphuza utshwala ekuzaleni kowesilisa lubonisa ukuthi ukusebenzisa utshwala isikhathi eside kunganciphisa ukukhiqizwa kwesidoda [8]. Olunye ucwaningo lubonisa ukuthi ukusebenzisa utshwala isikhathi eside kwehlisa amazinga e-testosterone [9]. I-testosterone ephansi ibangela ukukhiqizwa kwesidoda okuncishisiwe kanye nempilo embi yesidoda kubantu abahlaselwe utshwala.

5. Ama-Anabolic Steroid

I-anabolic steroid iwuhlobo lwemithi abantu abayisebenzisa kakhulu ukwakha imisipha nokushisa amafutha. Le mithi ifanekisela i-testosterone emzimbeni, okunciphisa ikhono lomzimba lokukhiqiza i-testosterone [10].

Ngokwehlisa amazinga e-testosterone esikhathini eside, ama-anabolic steroid athinta kabi izici zesidoda njengezinani zesidoda nokuma kwamasidoda.

Imithi Kadokotela Nezinani Zesidoda

Lokhu kungamangaza abaningi kodwa imithi yokudlulisela udokotela abayisebenzisayo kakhulu ezimeni ezahlukene zempilo ingaphinde yehlise inani lesidoda. Pho yimuphi umuthi ohlisa inani lesidoda? Imithi ehlisa inani lesidoda ihlanganisa:

1. Imithi Ye-Chemotherapy

Imithi ye-chemotherapy ivame ukusetshenziswa ekwelapheni umdlavuza. Le mithi ihlose amaseli ahlukanisa ngokushesha, okuhlanganisa namaseli akhiqiza isidoda emasendeni [11].

Ukuvinjwa kokuhlukana kwamaseli nokwakheka kwamaseli amasha yimithi ye-chemotherapy kungabangela inani lesidoda eliphansi okwesikhashana noma unomphela.

2. Imithi Yokudambisa Ukucindezeleka

Imithi yokudambisa ukucindezeleka noma ama-selective serotonin reuptake inhibitors (SSRIs) ingathinta ukuzala kowesilisa ngokunciphisa ukushukuma kocansi. Ucwaningo ngomthelela wama-SSRI ekhwalithi yesidoda lubonisa ukuthi le mithi ingathinta inani lesidoda, ukuma kwamasidoda, nokunyakaza kwamasidoda [12].

Ucwaningo luphinde luchaze ukuthi ama-SSRI angathinta ubuqotho be-DNA futhi enze kube nzima ukuthi indoda ikhulelise.

3. Ama-Opioid

Ama-opioid, okuyimithi ejwayelekile yokwelapha ubuhlungu, angaphazamisa ukukhiqizwa kwe-testosterone [13]. Lokhu kuphazamiseka kungaholela enanini eliphansi lesidoda.

Ama-opioid angaphinde anciphise isifiso socansi nokusebenza ocansini ngenxa yomthelela wawo ezimpawini zama-hormone. Lokhu kunganciphisa amathuba okukhulelwa emadodeni aphuza ama-opioid njalo.

4. Imithi Yomfutho Wegazi

Imithi yeziyobisi ehlisa inani lesidoda ihlanganisa nemithi yomfutho wegazi. Imithi yomfutho wegazi inganciphisa inani lesidoda ngokuthi ukunciphisa ukugeleza kwegazi eya kumasende. Ukuntuleka kokugeleza kwegazi okwanele kumaseli akhiqiza amasperm kwehlisa ikhono lawo lokukhiqiza amasperm.

Imithi yomfutho wegazi ingase futhi ithinte ukunyakaza kwamasperm, okwenza kube nzima ukuthi amasperm afinyelele iqanda alichumise. Ukuntuleka kokugeleza kwegazi okwanele esithweni sangasese sowesilisa kungaphazamisa nokuqina kwalo nokuvuka kocansi.

Isengezo Sokuthuthukisa Impilo yamasperm

Ngenkathi izidakamizwa eziningi zokuzijabulisa nezibhalwe udokotela zithinta kabi impilo yamasperm, zikhona izithasiselo ongazithatha ukuze uthuthukise impilo yamasperm namandla okuzala jikelele.

Ezinye zezincono kakhulu izithasiselo zokuzala zabesilisa zimi kanje:

Conceive Plus Fertility Support

Uma nizama ukukhulelwa kodwa unenani eliphansi lamasperm elibangelwa izidakamizwa, Conceive Plus Fertility Support izithasiselo zingakusiza. Lezi zithasiselo ziqukethe amavithamini nezimbiwa ezibalulekile umzimba wakho owazidingayo ukuze kukhiqizwe amasperm anempilo.

Izithako ezisemithini yokusekela ukuzala ezifana no-vitamin D, E, i-Zinc, ne-L-carnitine ziyi kufakazelwe ngesayensi ukuthuthukisa inani lamasperm nokwandisa impilo yokuzala yonkana kowesilisa.

Conceive Plus Motility Support

Conceive Plus Motility Support izithasiselo zakhelwe ngokukhethekile ukuthuthukisa ukunyakaza kwamasperm. Ukunyakaza kwamasperm kubalulekile ukuze amasperm akwazi ukubhukuda emgudwini wokuzala wesifazane afinyelele iqanda.

Ngaphezu kokuhamba kwamasperm, izithako ezikumasengezo okuthuthukisa ukunyakaza kwamasperm zingathuthukisa futhi inani lamasperm futhi zithuthukise impilo yokuzala yonke. 

Okubalulekile

Sivame ukuzwa ngemiphumela emibi emzimbeni nasekuphileni okuvamile ebangelwa ezinye izidakamizwa. Nokho, elinye iphupho elikhulu lemiphumela emibi yezinye izidakamizwa abantu abaningi abangazi ngalo, inani eliphansi lamasperm. Kodwa ingabe izidakamizwa zinciphisa inani lamasperm? Noma, uma sikhuluma ngokucacile, imiphi imithi enciphisa inani lamasperm? Noma imiphi imithi eyehlisa inani lamasperm?

Ubufakazi bubonisa ukuthi izidakamizwa ezahlukene zokuzijabulisa ezifana ne-marijuana, i-cocaine, notshwala zinganciphisa inani lamasperm futhi zithinte kabi impilo yamasperm. Le miphumela engemihle yezidakamizwa zokuzijabulisa ivame ukubangelwa indlela eziphazamisa ngayo ukukhiqizwa kwe-testosterone.

Akugcini nje ngezidakamizwa zokuzijabulisa, kodwa eminye imithi kadokotela inganciphisa inani lamasperm futhi ikwenze kube nzima ukuthi nikwazi ukukhulelwa. Sincoma ukuthi uxhumane nochwepheshe wezempilo ngaphambi kokuthatha yimuphi umuthi ongathinta amandla akho okuzala.

Izinsiza Ezisetshenzisiwe

1. Low sperm count - Ukuxilongwa nokwelashwa - Mayo Clinic. (2022, December 17). https://www.mayoclinic.org/diseases-conditions/low-sperm-count/diagnosis-treatment/drc-20374591
2. Srinivasan, M., Hamouda, R. K., Ambedkar, B., Arzoun, H. I., Sahib, I., Fondeur, J., Mendez, L. E., & Mohammed, L. (2021). Umphumela we-marijuana ekwenzeka nasekuguqukeni kokungazali emadodeni: ukubuyekezwa ohlelelekile. Cureus. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC8720305/
3. Barnett, G., Chiang, C. N., & Licko, V. (1983). Imiphumela ye-marijuana ku-testosterone kubantu besilisa. Journal of Theoretical Biology, 104(4), 685-692. https://doi.org/10.1016/0022-5193(83)90255-2
4. Nudmamud-Thanoi, S., & Thanoi, S. (2011). I-methamphetamine ibanga ukwakheka okungajwayelekile kwesidoda, ukugxila okuphansi kwesidoda kanye ne-apoptosis emathesthini amagundane ezilisa. Andrologia. Available at: https://onlinelibrary.wiley.com/doi/10.1111/j.1439-0272.2010.01071.x
5. Ukuqonda ukwakheka (morphology) kwesidoda nokuzala. Conceive Plus®. https://conceiveplus.com/blogs/blog/sperm-morphology-and-fertility
6. Samplaski, M. K., Bachir, B. G., Lo, K. C., Grober, E. D., Lau, S., & Jarvi, K. A. (2015). Ukusetshenziswa kwe-cocaine kubantu besilisa abangazali: uphawu lwezimo eziholela ekuncipheni kokuzala. Current Urology. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC4483290/
7. Ubufakazi bokungasebenzi kahle kwe-hypothalamic-pituitary-adrenal kanye ne-gonadal emadodeni athembeke ekuluthweni yi-cocaine. European Addiction Research. Available at: https://karger.com/ear/article/30/2/114/894138/Evidence-of-Hypothalamic-Pituitary-Adrenal-and
8. Finelli, R., Mottola, F., & Agarwal, A. (2021). Umthelela wokuphuza utshwala emandleni okuzala emadodeni: ukubuyekezwa okulandisayo. International Journal of Environmental Research and Public Health. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC8751073/
9. Koh, K., Kim, S. S., Kim, S., Jung, G., Yoon, J., Suh, W. Y., Kim, H. G., & Kim, N. (2022). Ubudlelwano phakathi kokuphuza utshwala nokushoda kwe-testosterone ngokusho kokubomvu kobuso emadodeni aseKorea aseminyakeni ephakathi nangaphezulu. Korean Journal of Family Medicine. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC9708857/
10. Rasmussen, J. J., Selmer, C., Østergren, P. B., Pedersen, K. B., Schou, M., Gustafsson, F., Faber, J., Juul, A., & Kistorp, C. (2016). Abantu ababengabahlukumezi bama-anabolic androgenic steroids ngaphambilini babonisa amazinga e-testosterone ancishisiwe nezimpawu ze-hypogonadism eminyakeni eminingi ngemuva kokuyeka: ucwaningo lwe-case-control. PLoS ONE. Available at: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0161208
11. Meistrich, M. L. (2013). Imiphumela ye-chemotherapy kanye ne-radiotherapy ekwakhekeni kwesidoda (spermatogenesis) kubantu. Fertility and Sterility. Available at: https://www.fertstert.org/article/S0015-0282(13)02955-5/fulltext
12. Xu, J., He, K., Zhou, Y., Zhao, L., Lin, Y., Huang, Z., Xie, N., Yue, J., & Tang, Y. (2022). Umphumela wama-SSRIs ekhwalithi yesidoda: ukubuyekezwa ohlelelekile kanye ne-meta-analysis. Frontiers in Pharmacology. Available at: https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.911489/full
13. Safarinejad, M. R., Asgari, S. A., Farshi, A., Ghaedi, G., Kolahi, A. A., Iravani, S., & Khoshdel, A. R. (2013). Imiphumela yokusetshenziswa kwama-opiate ezingeni lama-hormone okuvelisa egazini, iziparamitha zesidoda, amandla e-antioxidant e-seminal plasma kanye nokuthembeka kwe-DNA yesidoda. Reproductive Toxicology, 36, 18-23. https://doi.org/10.1016/j.reprotox.2012.11.010