Yini Uketshezi Lwesidoda Olungazali Futhi Luhlobene Kanjani Ne-Azoospermia
Ukuzama ukuba nomntwana kungaba nzima. Ikakhulukazi uma izinto zingahambi ngendlela eniyethemba ngayo. Enye yezinkinga ezinkulu ezinye izibini ezibhekana nazo ukungasebenzi kahle koketshezi lwesidoda, okunganciphisa amathuba okukhulelwa. Lokhu kuvame ukuhlotshaniswa nesimo esibizwa ngokuthi i-azoospermia. Kodwa kusho ukuthini ngempela igama elithi azoospermia? Ngamafuphi, kusho ukuthi akukho sidoda eketshezini lwesidoda. Kule ndatshana, sizohlola izimpawu ze-azoospermia, izimbangela, nezinhlobo zokwelashwa, nokuthi ixhumene kanjani nokungasebenzi kahle koketshezi lwesidoda.
Incazelo Nencazelo Yegama Elithi Azoospermia
Okokuqala, ake sikhulume ngokuchazwa kwe-azoospermia. Ngamazwi alula, kuwukuthi akukho nhlobo sidoda eketshezini lwesidoda. Lesi simo sivamile kakhulu ukwedlula ocabanga ngakho. Sithinta cishe u-1% wamadoda, kodwa uma kukhulunywa ngamadoda abhekene nokungazali, sitholakala ku-10-15% wabo [1]. Ukuze uqonde kahle lesi simo, kudingeka uchaze ukuthi yini i-azoospermia. Ngokuchazwa kwe-azoospermia, ihlukaniswe ngezigaba ezintathu: i-pre-testicular, i-testicular, kanye ne-obstructive azoospermia.
- I-pre-testicular azoospermia: Amabele asebenza kahle, kodwa umzimba awuthumeli imisindo yama-hormone efanele yokwenza isidoda.
- I-testicular azoospermia: Lokhu kwenzeka uma kunenkinga ngaphakathi emabeleni uqobo, okumisa ukukhiqizwa okuvamile kwesidoda.
- I-obstructive azoospermia: Isidoda siyakhiqizwa, kodwa kukhona ukuvinjelwa okungenza singahlangani noketshezi lwesidoda.
Iseluleko Esiphezulu: Uma nibe nizama ukukhulelwa isikhathi eside kungaphumeleli, kuwufanele ukucela udokotela ahlole i-azoospermia.
Yiziphi Izimpawu Ze-Azoospermia?
Nansi inkinga—izimpawu ze-azoospermia azihlali zicacile. Eqinisweni, amadoda amaningi awazi lutho ukuthi ayinayo kuze kube sebefuna ukuchuma kodwa akukho okwenzekayo. Imvamisa akukho buhlungu noma okuzwayo kungahambi kahle. Amanye amadoda angase aqaphele izinto ezifana nokwehla kwesifiso socansi noma ubunzima bokufinyelela noma bokugcina ukuvuvukala kwezitho zobulili, kodwa kaningi akukho zimpawu kuze kwenziwe ukuhlolwa kokungachumi [2].
Umyeni Wami Akanasododa Ngingakhulelwa Kanjani?
Lena inzima. Imibhangqwana eminingi iphetha isibuza, "umyeni wami akanasidoda ngingakhulelwa kanjani?" Umbuzo wesabekayo lo, kodwa kukhona ongakwenza. Uma kubangelwa i-obstructive azoospermia, ukuhlinzwa kwesinye isikhathi kungasusa ukuvinjelwa, kuvumele isidoda siphinde sigijime. Ezimeni lapho ukuhlinzwa kungenzeki, noma isidoda singakhiqizwanga nhlobo, odokotela bangasebenzisa izindlela zokukhipha isidoda ngqo emabeleni (emaphini). Leso sidoda singase sisetshenziselwe i-IVF (in vitro fertilization). Akulula njalo, kodwa kusekhona ithuba lokukhulelwa [3].
Ithiphu Eyinhloko: Uma umlingani wakho ene-azoospermia, ukuhlola izinketho ezifana ne-IVF nokukhipha isidoda kungaba yimpendulo oyifunayo.
Izimbangela Ze-Azoospermia
Ake sikhulume ngezimbangela ze-azoospermia. Zincike ohlotsheni lwe-azoospermia esibhekene nalo. Uma kuyeyangaphambi kwesende (pre-testicular), khona-ke izinkinga zama-hormone noma ukwelashwa kwezokwelapha okufana ne-chemotherapy kungaba inkinga. Uma sekuyiyo i-testicular azoospermia, amasende uqobo angase alimale ngenxa yezifo, ukulimala, noma izifo zofuzo. Bese-ke, nge-obstructive azoospermia, ukuvinjelwa emgudwini wokuzala—okungenzeka kube ngenxa yokuhlinzwa, izifo, noma ngisho nesimo esinjenge-cystic fibrosis—yizona zibangela eziyinhloko [4].
Izinketho Zokwelapha I-Azoospermia
Ngakho-ke, hlobo luni lokwelashwa lwe-azoospermia olukhona? Yebo, kuya ngohlobo lwe-azoospermia. Uma kuyiyo i-obstructive azoospermia, ukuhlinzwa kwesinye isikhathi kungalungisa ukuvinjelwa, kuvumele isidoda ukuba sikhululwe. Ezimeni zangaphambi kwesende, ukwelashwa nge-hormone kungasiza ukukhuthaza ukukhiqizwa kwesidoda. Kuthi-ke ezinkingeni zesende uqobo? Kukhona amasu okukhipha isidoda ngqo emasendenini, esingasetshenziswa ku-IVF noma kwezinye izindlela zobuchwepheshe bokuzala. Ngisho nabesilisa abakhiqiza isidoda esincane kakhulu bangazuza kulezi zinhlobo zokwelashwa ezithuthukile [5].
Uma uzibuza, "inani lami lesidoda linguziro, ngilikhuphula kanjani," izinketho ezifana nokwelashwa nge-hormone noma izinguquko endleleni yokuphila zingasiza. Futhi ngezinye izikhathi, ukwengeza amasuplementi afana ne-Zinc, CoQ10, noma i-L-Carnitine kungathuthukisa impilo yesidoda, kwenze umehluko wangempela.
Izimpawu Zesidoda Esifile Nokuchaza Kwazo Ekukhiqizeni Izingane
Izimpawu zesidoda esifile zihlukile kancane ku-azoospermia. Kulokhu, isidoda sikhona, kodwa asiphili futhi asikwazi ukuchumisa iqanda. Lokhu kungatholakala ngokwenza uhlaziyo lwesidoda. Nakuba lokhu kungase kuzwakale kudikibalisa, ukwelashwa okunjenge-IVF ene-ICSI (intracytoplasmic sperm injection) kusengakunikeza indlela eya ekukhulelweni ngokujova isidoda elisebenzayo ngqo eqandeni [6]. Uma uzibuza ukuthi inani lesidoda lithinta kanjani ukukhulelwa, ukuqonda ukuthi inani lesidoda lithinta kanjani ukuzala kungakusiza uqondiswe ezinyathelweni zakho ezilandelayo.
Ukungakwazi Ukwakha Isidoda: Yini Elandelayo?
Ukubhekana nokungakwazi ukukhiqiza isidoda kungazwakala kusinda kakhulu. Lokhu kusebenza emadodeni anayo i-azoospermia engeyona eyokuvinjelwa. Kule madoda, amasende awenzi isidoda esanele, noma awenzi nhlobo. Kodwa noma bengakhiqizi isidoda, kusenokholo. Izobuchwepheshe bokuzala obuthuthukile kwesinye isikhathi bungathola inani elincane lesidoda, elingasetshenziswa ezinqubweni zokuzala ezisizwa. Noma lingaba lincane kangakanani, linganele kwi-IVF [7].
Okubalulekile
Isidoda esingabi nenzalo kanye ne-azoospermia kungakwenza kube nzima ukukhulelwa, kodwa akusho ukuphela kwethemba lakho lokuba nomndeni. Kusukela ekuhlinzweni kuya ekwelashweni ngehomoni kuya kwezobuchwepheshe bokuzala obuthuthukile njengokuthi i-IVF, kukhona izinketho. Uma uhlangabezana nokungakhiqizi isidoda noma noma yiziphi izimpawu ze-azoospermia, ukubona udokotela kusenesikhathi kubalulekile. Uma wazi ngokushesha okwenzekayo, ngokushesha uqala ukusebenza ekutholeni isixazululo.
Imibuzo Evame Ukubuzwa
Kuyini incazelo ye-azoospermia?
I-Azoospermia isho ukuthi asikho nhlobo isidoda esikhona esidodeni, okwenza kube nzima ukukhulelwa ngendlela yendabuko.
Inani lesidoda sami linguziro, ngingalikhipha kanjani?
Ukwelashwa ngehomoni, ukuhlinzwa, noma izithasiselo ezifana ne-Zinc ne-CoQ10 kungasiza ukwandisa inani lesidoda kwezinye izimo.
Ziyini izimpawu zesidoda esifile?
Isidoda esifile sibhekisela kusidoda esikhona kodwa esingasebenzi. Lokhu kungatholakala ngokuhlaziywa kwesidoda (semen analysis).
Ingabe ukukhiqizwa kwesidoda okuncane kungaholela ekungabi nenzalo?
Yebo, ukuba nenani eliphansi lesidoda kunganciphisa amathuba okukhulelwa, kodwa kukhona izindlela zokwelapha.
Yiliphi igama lezokwelapha elisho isimo sokungabikho kwesidoda?
Igama lesimo lesi yi-azoospermia.
Izinkomba
- Leslie SW, Soon-Sutton TL, Khan MAB. Ukungabi nenzalo kwabesilisa. StatPearls. Kutholakala ku: https://www.ncbi.nlm.nih.gov/books/NBK562258/
- Cocuzza M, Alvarenga C, Pagani R. I-epidemiology nezimbangela ze-azoospermia. Clinics. Kutholakala ku: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583160/
- Sharlip ID, Jarow JP, Belker AM, Lipshultz LI, Sigman M, Thomas AJ, Schlegel PN, Howards SS, Nehra A, Damewood MD, Overstreet JW, Sadovsky R. Izinqubomgomo ezihamba phambili ekwelapheni ukungabi nenzalo kwabesilisa. Fertil Steril. Kutholakala ku: https://pubmed.ncbi.nlm.nih.gov/12009338/
- Amory JK, Bremner WJ. Ukulawulwa komsebenzi wamasende emadodeni: imiphumela ekuthuthukisweni kwemithi yokuvimbela inzalo yohlelo lwehomoni lwabesilisa. J Steroid Biochem Mol Biol. Kutholakala ku: https://pubmed.ncbi.nlm.nih.gov/12943722/#:~:text=Precise%20regulation%20of%20testicular%20function,and%20modulated%20by%20testicular%20hormones.
- Esteves SC, Miyaoka R, Orosz JE, Agarwal A. Isibuyekezo ngezindlela zokuthola isidoda kwabesilisa abane-azoospermia. Clinics (Sao Paulo). Kutholakala ku: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583154/
- Palermo GD, O'Neill CL, Chow S, Cheung S, Parrella A, Pereira N, Rosenwaks Z. Ukufakwa kwesidoda ngaphakathi kwesitho sowesifazane (intracytoplasmic sperm injection): isimo esiphambili kubantu. Reproduction. Kutholakala ku: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719728/
- Ishikawa T. Ukubuyiselwa kwesidoda ngokuhlinzwa ku-azoospermia engeyona eyokuvinjelwa. Asian J Androl. Kutholakala ku: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735145/
