Sperm quality may impact offspring
Men who wait longer to have children run an increased risk of passing on potential health conditions to their offspring due to sperm health, a new study from University of Otago has found.
The study analyzed the results of 90 existing studies on male fertility and found consistent findings—the quality of a man’s semen declined as he aged.
Not only did older sperm increase the risk of miscarriage and other complications during pregnancy, they increased the likelihood of a range of conditions such as Autism, Down syndrome, epilepsy and schizophrenia. It could also be a big factor in infertility.The study was not designed to identify the rate of decline, but Johnson said existing studies showed that consistent downward trend could begin as early as 35.
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The specific problem with older semen was lower volume, poor sperm performance, and increases in malformed and DNA-damaged sperm. Semen quality is used to show how fertile a man is. However instead of relying on semen volume, sperm concentration and total sperm count, which are common clinically measured traits, Johnson said a greater focus on the ratio of DNA-fragmented sperm cells and their ability to swim, could be more important aspects of sperm quality: these are likely more accurate and consistent predictors of a man’s fertility status.The findings were significant because many couples were waiting longer to have children, Johnson said.
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