Can You Use Lubricant During IVF or IUI? What Fertility Doctors Recommend
The Short Answer
Yes — but only a sperm-safe, fertility-specific lubricant. Standard lubricants should never be used during fertility treatments. Conceive Plus Fertility Lubricant is FDA cleared and is recommended by fertility specialists and reproductive endocrinologists for use during IVF and IUI cycles.
Why Regular Lubricant Is Harmful During IVF and IUI
During IVF and IUI, sperm quality is critically important. Standard lubricants — including KY Jelly, Astroglide, and most water-based gels — have been shown to reduce sperm motility by 60–100% within 30 minutes of contact. For couples investing in assisted reproduction, using the wrong lubricant can directly compromise results.
The American Society for Reproductive Medicine (ASRM) advises that couples trying to conceive avoid conventional lubricants and use only fertility-compatible products.
What Fertility Clinics Recommend
Fertility clinics recommend lubricants that are:
- Isotonic — matched to the osmolarity of cervical fluid
- pH-balanced — between 7.2 and 8.2 (the range in which sperm function optimally)
- Free of spermicidal ingredients — no nonoxynol-9, high-concentration parabens, or glycerin
- Clinically validated — with published evidence of sperm compatibility
Conceive Plus Fertility Lubricant meets all of these criteria and is FDA cleared under 510(k) K131355.
Conceive Plus and IVF/IUI: What You Need to Know
During IVF: Conceive Plus can be used during the natural intercourse component of IVF (where applicable) or during the stimulation phase when natural lubrication may be reduced due to medication. It does not interfere with ovarian stimulation drugs, trigger shots, or the implantation process.
During IUI: Conceive Plus can be used in the days leading up to IUI and on the day of the procedure (before the clinical appointment). It does not affect sperm washing procedures.
During the two-week wait: Conceive Plus can be used safely during the luteal phase after IUI or embryo transfer. It does not disrupt the uterine environment.
Frequently Asked Questions
Is Conceive Plus safe for use with fertility medications (Clomid, Letrozole, Gonal-F)?
Yes. Conceive Plus does not interact with fertility medications. It is a physical lubricant — not a drug — and its ingredients do not affect hormonal pathways or medication efficacy.
Can I use Conceive Plus after embryo transfer?
Yes. Conceive Plus can be used after embryo transfer. It does not affect implantation and has no spermicidal or hormonal properties.
Do I need a prescription for Conceive Plus?
No. Conceive Plus is available over the counter without a prescription, online and in pharmacies in 70+ countries.
Is Conceive Plus recommended by fertility doctors?
Yes. Conceive Plus is recommended by OBGYNs, reproductive endocrinologists, and fertility specialists globally. Many fertility clinics include it in their patient resource guides.
Summary
If you are undergoing IVF or IUI, choose your lubricant carefully. Regular lubricants can harm sperm and reduce your chances of success. Conceive Plus Fertility Lubricant is FDA cleared, clinically validated to maintain 99% sperm viability, and safe for use throughout fertility treatment.





